NQO1 monoclonal antibody, clone A180
产品名称： NQO1 monoclonal antibody, clone A180
英文名称： NQO1 monoclonal antibody, clone A180
产品编号： MAB2302
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against full length recombinant NQO1.
- Immunogen:
- Recombinant protein corresponding to full length human NQO1.
- Host:
- Mouse
- Reactivity:
- Dog, Human, Primates, Rat
- Specificity:
- This antibody is specific to NQO1.
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In Tris-glycine, 150 mM NaCl
- Storage Instruction:
- Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- trans-Stilbene oxide induces expression of genes involved in metabolism and transport in mouse liver via CAR and Nrf2 transcription factors.
Slitt AL, Cherrington NJ, Dieter MZ, Aleksunes LM, Scheffer GL, Huang W, Moore DD, Klaassen CD.Mol Pharmacol. 2006 May;69(5):1554-63. Epub 2006 Jan 31.
- 2.
- Immunohistochemical detection of NAD(P)H:quinone oxidoreductase in human lung and lung tumors.
Siegel D, Franklin WA, Ross D.Clin Cancer Res. 1998 Sep;4(9):2065-70.
- Application Image
- Western Blot (Cell lysate)
- enlarge
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunofluorescence
- Immunoprecipitation
- Entrez GeneID:
- 1728
- Gene Name:
- NQO1
- Gene Alias:
- DHQU,DIA4,DTD,NMOR1,NMORI,QR1
- Gene Description:
- NAD(P)H dehydrogenase, quinone 1
- Omim ID:
- 125860
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
- Other Designations:
- DT-diaphorase,NAD(P)H menadione oxidoreductase 1, dioxin-inducible,NAD(P)H:Quinone acceptor oxidoreductase type 1,NAD(P)H:menadione oxidoreductase 1,NAD(P)H:quinone oxireductase,azoreductase,diaphorase (NADH/NADPH) (cytochrome b-5 reductase),diaphorase-4,
- Related Disease
- Acquired Immunodeficiency Syndrome
- Acute Disease
- Acute Lung Injury
- Adenocarcinoma
- Adenoma
- Adenoma, Liver Cell
- Akathisia, Drug-Induced
- Alcohol Withdrawal Delirium
- Alzheimer Disease
- Alzheimer disease
- Anemia, Aplastic
- Aneuploidy
- Angina Pectoris
- Asthma
- Asthma
- Atherosclerosis
- Atherosclerosis
- Atrophy
- Balkan Nephropathy