补体4结合蛋白-抗体-抗体-生物在线
北京索莱宝科技有限公司
补体4结合蛋白

补体4结合蛋白

商家询价

产品名称: 补体4结合蛋白

英文名称: C4 binding protein

产品编号: bs-15184R

产品价格: null

产品产地: 北京

品牌商标: BIOSS

更新时间: 2025-07-01T13:44:12

使用范围: WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,

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C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants